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Research in Biochemistry - Parasitism

Picture of a parasited manduca, from University of WashingtonParasites are organisms that grow or feed in or on a "host" organism without providing any benefit to the host. In nature, tiny wasps of thePolistes family puncture the skin of Manduca larvae and lay their eggs. When the eggs hatch, the wasp larvae burrow back out through the skin and attach themselves to the caterpillar. There, they "hitch a ride", feeding off the Manduca larva until they reach adulthood.

The important feature of this parasitic relationship is that the Manduca larvae's normally strongPicture of parasited Manduca from Clemson University immune system fails to notice that it has been invaded.Researchers have found that, along with the eggs, the wasp injects a virus that interferes with the Manducas immune response. These wasps are already used in agriculture as a part of integrated pest management, for controlling the plant-munching Manduca.

Scientists are trying to better understand the biochemical process by which the virus works, in hopes of using this knowledge to develop better and safer pest control techniques, and more effective treatments of immune system disorders in humans.

 

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